owmeta.channelworm module¶

class owmeta.channelworm.ChannelModel(modelType=None, *args, **kwargs)[source]¶

Bases: owmeta_core.dataobject.DataObject

A model for an ion channel.

There may be multiple models for a single channel.

Example usage:

>>> from owmeta_core.quantity import Quantity

# Create a ChannelModel
>>> cm = PatchClampChannelModel(key='ca_boyle',
...     gating='voltage',
...     ion='Ca',
...     conductance=Quantity.parse('10pS'))

conductance¶: The conductance of this ion channel. This is the initial value, and should be entered as a Quantity object.

gating¶: The gating mechanism for this channel (“voltage” or name of ligand(s) )

ion¶: The type of ion this channel selects for

modelType¶: The type of model employed to describe a channel

neuroML¶: Property for attaching NeuroML documents to resources

class owmeta.channelworm.HomologyChannelModel(**kwargs)[source]¶: Bases: owmeta.channelworm.ChannelModel

class owmeta.channelworm.PatchClampChannelModel(**kwargs)[source]¶: Bases: owmeta.channelworm.ChannelModel

class owmeta.channelworm.PatchClampExperiment(**kwargs)[source]¶

Bases: owmeta.experiment.Experiment

Store experimental conditions for a patch clamp experiment.

Ca_concentration¶: Calcium concentration

Cl_concentration¶: Chlorine concentration

blockers¶: Channel blockers used for this experiment

cell¶: The cell this experiment was performed on

cell_age¶: Age of the cell

initial_voltage¶: Starting voltage of the patch clamp

ion_channel¶: The ion channel being clamped

membrane_capacitance¶: Initial membrane capacitance

mutants¶: Type(s) of mutants being used in this experiment

patch_type¶: Type of patch clamp being used (‘voltage’ or ‘current’)

pipette_solution¶: Type of solution in the pipette